Mini Mental Status Exam (MMSE)


Mini Mental Status Exam (MMSE)
·       Level of Consciousness
o   Ask: Year, season, day, date, month
o   What is tested?: Consciousness is impaired in damage to the brainstem reticular formation, bilateral thalami or cerebral hemispheres
·       Orientation.
o   Ask for patient’s full name, location and date
o   What is tested?: recent and long-term memory
·       Memory
o   Ask patient to recall three items for a delay of 3 to 5 minutes
o   What is tested?:
§  Medial temporal lobe and medial diencephalon
·       Damage leads to intact immediate recall, difficulty after delay
·       Anterograde and retrograde amnesia with sparing of earlier memories
§  loss of memory without these time characteristics may signify damage to other areas
·       Language
o   Ask patient to name pencil and watch. Read and obey the following “CLOSE YOUR EYES”
o   What is tested?: Broca’s and Wernicke’s area
·       Calculations, right-left confusion, finger agnosia, agraphia
o   Ask patient to complete serial 7’s, WORLD backwards
o   What is tested?: dominant parietal lobe
·       Apraxia
o   Ask patient to perform 3 stage command “take a paper in your hand, fold it in half and put it on the floor”
o   Inability to follow a motor command that is not due to a primary motor deficit or a language impairment but caused by a deficit in higher-order planning or conceptualization of the task
o   What is tested?:
§  localizing is difficult because many different regions may be involved
§  commonly present in lesions affecting the language areas and adjacent structures of the dominant hemisphere making it difficult to prove the deficit is apraxia rather than impaired language comprehension
§  Distinction can often be made by asking patient to perform a task, then if they fail, demonstrating several tasks and asking them to choose the correct one
·       Neglect and Constructions
o   What is tested?: right (nondominant) parietal lobe; much milder neglect may occur from lesions to left parietal lobe
·       Sequencing tasks and frontal release signs
o   What is tested?: frontal lobe
·       Mood
What is tested?: imbalances in neurotransmitter systems

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